Journal article
Reversible ligation of programmed DNA-gold nanoparticle assemblies
- Abstract:
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We demonstrate a new method to reversibly cross-link DNA-nanoparticle dimers, trimers, and tetramers using light as an external stimulus. A DNA interstrand photo-cross-linking reaction is possible via ligation of a cyano-vinyl carbazole nucleoside with an opposite thymine when irradiated at 365 nm. This reaction results in nanoparticle assemblies that are not susceptible to DNA dehybridization conditions. The chemical bond between the two complementary DNA strands can be reversibly broken upo...
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- Publication status:
- Published
- Peer review status:
- Peer reviewed
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- Files:
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(Accepted manuscript, pdf, 1.3MB)
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- Publisher copy:
- 10.1021/jacs.5b05683
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Authors
Funding
+ Engineering and Physical Sciences Research Council
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Grant:
EP/G060363/1
EP/K503575/1
Defence Science and Technology Laboratory
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Bibliographic Details
- Publisher:
- American Chemical Society Publisher's website
- Journal:
- Journal of the American Chemical Society Journal website
- Volume:
- 137
- Issue:
- 29
- Pages:
- 9242-9245
- Publication date:
- 2015-07-20
- DOI:
- EISSN:
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1520-5126
- ISSN:
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0002-7863
- Source identifiers:
-
535136
Item Description
- Language:
- English
- Pubs id:
-
pubs:535136
- UUID:
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uuid:cdf45448-96fd-4dcb-948d-fa4e1da0e84d
- Local pid:
- pubs:535136
- Deposit date:
- 2016-03-01
Terms of use
- Copyright holder:
- American Chemical Society
- Copyright date:
- 2015
- Notes:
- © 2015 American Chemical Society. This is the accepted manuscript version of the article. The final version is available online from the American Chemical Society at: [10.1021/jacs.5b05683]
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