Journal article
Prognostic value, localization and correlation of PD-1/PD-L1, CD8 and FOXP3 with the desmoplastic stroma in pancreatic ductal adenocarcinoma.
- Abstract:
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We examined the prognostic value of programmed cell death-1 (PD-1) and its ligand (PD-L1) together with CD8+ tumor-infiltrating lymphocytes (TILs) and FOXP3+ Tregs in resectable pancreatic ductal adenocarcinoma (PDAC) samples treated with adjuvant chemotherapy. Whole-mount FFPE tissue sections from 145 pancreatectomies were immunohistochemically stained for PD-1, PD-L1, CD8 and FOXP3. Their expression was correlated with clinicopathological characteristics, and overall survival (OS), progress...
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- Publication status:
- Published
- Peer review status:
- Peer reviewed
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(Version of record, pdf, 2.7MB)
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- Publisher copy:
- 10.18632/oncotarget.10038
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Authors
Funding
Cancer Research UK
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Marie Curie Innovative Training Network
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Kidani Memorial Trust
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Bibliographic Details
- Publisher:
- Impact Journals Publisher's website
- Journal:
- Oncotarget Journal website
- Publication date:
- 2016-06-14
- Acceptance date:
- 2016-05-14
- DOI:
- EISSN:
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1949-2553
- Source identifiers:
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631017
Item Description
- Language:
- English
- Keywords:
- Pubs id:
-
pubs:631017
- UUID:
-
uuid:cde9a669-db83-4b09-b31e-b58bee5395b8
- Local pid:
- pubs:631017
- Deposit date:
- 2016-07-05
Terms of use
- Copyright holder:
- Diana et al
- Copyright date:
- 2016
- Notes:
- © 2016 Diana et al. Published by Impact Journals. This article is licensed under a Creative Commons Attribution 3.0 License. The final version is available online from Impact Journals at: [10.18632/oncotarget.10038]
- Licence:
- CC Attribution (CC BY)
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