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Journal article

Modeling the heart--from genes to cells to the whole organ.

Abstract:

Successful physiological analysis requires an understanding of the functional interactions between the key components of cells, organs, and systems, as well as how these interactions change in disease states. This information resides neither in the genome nor even in the individual proteins that genes code for. It lies at the level of protein interactions within the context of subcellular, cellular, tissue, organ, and system structures. There is therefore no alternative to copying nature and ...

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Publication status:
Published

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Publisher copy:
10.1126/science.1069881

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Institution:
University of Oxford
Department:
Oxford, MSD, Physiology Anatomy and Genetics
Journal:
Science (New York, N.Y.)
Volume:
295
Issue:
5560
Pages:
1678-1682
Publication date:
2002-03-05
DOI:
EISSN:
1095-9203
ISSN:
0036-8075
URN:
uuid:cde598fc-2431-4c5a-948f-e98f61b61580
Source identifiers:
237617
Local pid:
pubs:237617

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