Journal article
A comparative analysis of whole genome sequencing of esophageal adenocarcinoma pre- and post-chemotherapy
- Abstract:
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The scientific community has avoided using tissue samples from patients that have been exposed to systemic chemotherapy to infer the genomic landscape of a given cancer. Esophageal adenocarcinoma is a heterogeneous, chemoresistant tumor for which the availability and size of pretreatment endoscopic samples are limiting. This study compares whole-genome sequencing data obtained from chemo-naive and chemo-treated samples. The quality of whole-genomic sequencing data is comparable across all sam...
Expand abstract
- Publication status:
- Published
- Peer review status:
- Peer reviewed
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(Version of record, pdf, 1.5MB)
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- Publisher copy:
- 10.1101/gr.214296.116
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Authors
Contributors
+ Davies, J
Institution:
University of Oxford
Division:
MPLS
Department:
Computer Science
Oxford college:
Kellogg College
Role:
Contributor
Funding
Biomedical Research Centre and the Experimental Cancer Medicine Centre
More from this funder
Bibliographic Details
- Publisher:
- Cold Spring Harbor Laboratory Press Publisher's website
- Journal:
- Genome Research Journal website
- Volume:
- 27
- Issue:
- 6
- Pages:
- 902-912
- Publication date:
- 2017-05-02
- Acceptance date:
- 2017-04-06
- DOI:
- EISSN:
-
1549-5469
- ISSN:
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1088-9051
- Pmid:
-
28465312
- Source identifiers:
-
692314
Item Description
- Language:
- English
- Pubs id:
-
pubs:692314
- UUID:
-
uuid:cddad6a5-fa7f-4adb-a937-b8b7c1292786
- Local pid:
- pubs:692314
- Deposit date:
- 2018-08-15
Terms of use
- Copyright holder:
- Noorani et al
- Copyright date:
- 2017
- Notes:
-
Copyright © 2017 Noorani et al.; Published by Cold Spring Harbor Laboratory Press
This article, published in Genome Research, is available under a Creative Commons License (Attribution 4.0 International), as described at http://creativecommons.org/licenses/by/4.0/.
- Licence:
- CC Attribution (CC BY)
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