Journal article
UMOD-ulating CKD risk: untangling the relationship between urinary uromodulin, blood pressure, and kidney disease
- Abstract:
-
A new Mendelian randomization study finds evidence that genetically predicted higher levels of urinary uromodulin are associated with lower kidney function and higher blood pressure. Bidirectional and multivariable Mendelian randomization suggests the association with higher blood pressure appears to be partially through decreased kidney function, but blood pressure does not appear to mediate the association of uromodulin with low kidney function. We describe the methods used for the bidirect...
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- Publication status:
- Published
- Peer review status:
- Peer reviewed
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- Publisher copy:
- 10.1016/j.kint.2021.09.019
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Authors
Bibliographic Details
- Publisher:
- Elsevier Publisher's website
- Journal:
- Kidney International Journal website
- Volume:
- 100
- Issue:
- 6
- Pages:
- 1168-1170
- Publication date:
- 2021-11-18
- Acceptance date:
- 2021-09-24
- DOI:
- EISSN:
-
1523-1755
- ISSN:
-
0085-2538
Item Description
- Language:
- English
- Keywords:
- Pubs id:
-
1210448
- Local pid:
- pubs:1210448
- Deposit date:
- 2021-11-18
Terms of use
- Copyright holder:
- International Society of Nephrology.
- Copyright date:
- 2021
- Rights statement:
- © 2021 International Society of Nephrology. Published by Elsevier Inc. All rights reserved.
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