Journal article
How the Hodgkin-Huxley equations inspired the Cardiac Physiome Project.
- Abstract:
- Early modelling of cardiac cells (1960-1980) was based on extensions of the Hodgkin-Huxley nerve axon equations with additional channels incorporated, but after 1980 it became clear that processes other than ion channel gating were also critical in generating electrical activity. This article reviews the development of models representing almost all cell types in the heart, many different species, and the software tools that have been created to facilitate the cardiac Physiome Project.
- Publication status:
- Published
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Authors
Bibliographic Details
- Journal:
- Journal of physiology
- Volume:
- 590
- Issue:
- Pt 11
- Pages:
- 2613-2628
- Publication date:
- 2012-06-01
- DOI:
- EISSN:
-
1469-7793
- ISSN:
-
0022-3751
- Source identifiers:
-
322988
Item Description
- Language:
- English
- Keywords:
- Pubs id:
-
pubs:322988
- UUID:
-
uuid:cdd4d35d-9fe9-40ad-81de-bd8145207bcd
- Local pid:
- pubs:322988
- Deposit date:
- 2013-11-16
Terms of use
- Copyright date:
- 2012
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