Journal article icon

Journal article

How the Hodgkin-Huxley equations inspired the Cardiac Physiome Project.

Abstract:
Early modelling of cardiac cells (1960-1980) was based on extensions of the Hodgkin-Huxley nerve axon equations with additional channels incorporated, but after 1980 it became clear that processes other than ion channel gating were also critical in generating electrical activity. This article reviews the development of models representing almost all cell types in the heart, many different species, and the software tools that have been created to facilitate the cardiac Physiome Project.
Publication status:
Published

Actions


Access Document


Authors


More by this author
Institution:
University of Oxford
Division:
MSD
Department:
Physiology Anatomy & Genetics
Role:
Author
More by this author
Institution:
University of Oxford
Division:
MSD
Department:
Physiology Anatomy & Genetics
Role:
Author
Journal:
Journal of physiology
Volume:
590
Issue:
Pt 11
Pages:
2613-2628
Publication date:
2012-06-01
DOI:
EISSN:
1469-7793
ISSN:
0022-3751
Source identifiers:
322988
Language:
English
Keywords:
Pubs id:
pubs:322988
UUID:
uuid:cdd4d35d-9fe9-40ad-81de-bd8145207bcd
Local pid:
pubs:322988
Deposit date:
2013-11-16

Terms of use


Views and Downloads






If you are the owner of this record, you can report an update to it here: Report update to this record

TO TOP