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Drosophila as a model system to unravel the layers of innate immunity to infection.

Abstract:

Innate immunity relies entirely upon germ-line encoded receptors, signalling components and effector molecules for the recognition and elimination of invading pathogens. The fruit fly Drosophila melanogaster with its powerful collection of genetic and genomic tools has been the model of choice to develop ideas about innate immunity and host-pathogen interactions. Here, we review current research in the field, encompassing all layers of defence from the role of the microbiota to systemic immun...

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Publication status:
Published

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Publisher copy:
10.1098/rsob.120075

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Institution:
University of Oxford
Division:
MSD
Department:
Biochemistry
Role:
Author
Journal:
Open biology
Volume:
2
Issue:
5
Pages:
120075
Publication date:
2012-05-01
DOI:
EISSN:
2046-2441
ISSN:
2046-2441
Source identifiers:
341119

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