Journal article icon

Journal article

Influences of CYP2D6*10 polymorphisms on the pharmacokinetics of iloperidone and its metabolites in Chinese patients with schizophrenia: a population pharmacokinetic analysis

Abstract:

Aim: Iloperidone is an atypical antipsychotic drug that is mainly metabolized by CYP2D6, CYP3A4, and cytosolic enzymes. Previous studies show that extensive and poor metabolizers of CYP2D6 exhibit different plasma concentrations of iloperidone and its metabolites. The aim of this study was to develop a pare...

Expand abstract
Publication status:
Published
Peer review status:
Peer reviewed

Actions


Access Document


Publisher copy:
10.1038/aps.2016.96

Authors


Expand authors...
National Key Clinical Specialist Construction Programs of China More from this funder
Expand funders...
Publisher:
Nature Publishing Group Publisher's website
Journal:
Acta Pharmacologica Sinica Journal website
Volume:
37
Pages:
1499–1508
Publication date:
2016-09-26
Acceptance date:
2016-06-24
DOI:
EISSN:
1745-7254
ISSN:
1671-4083
Pubs id:
pubs:826938
URN:
uri:cdac6a26-3daf-468b-83bc-87a63fcd1a30
UUID:
uuid:cdac6a26-3daf-468b-83bc-87a63fcd1a30
Local pid:
pubs:826938

Terms of use


Metrics



If you are the owner of this record, you can report an update to it here: Report update to this record

TO TOP