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Evidence of a chronic systemic cause of instability of atherosclerotic plaques.

Abstract:

BACKGROUND: Major thrombotic and embolic complications of atherosclerosis are closely associated with irregularity and rupture of atheromatous plaques in both the carotid and coronary arteries. Plaque instability is partly determined by local factors, but systemic factors, such as infection, autoimmunity, or genes, may also be important. If plaque stability is influenced by systemic factors that are present in only a proportion of patients, some individuals should be more prone to rupture of ...

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Publication status:
Published

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Institution:
University of Oxford
Division:
MPLS
Department:
Engineering Science
Sub department:
Institute of Biomedical Engineering
Role:
Author
Journal:
Lancet
Volume:
355
Issue:
9197
Pages:
19-24
Publication date:
2000-01-01
DOI:
EISSN:
1474-547X
ISSN:
0140-6736
Source identifiers:
244477
Language:
English
Keywords:
Pubs id:
pubs:244477
UUID:
uuid:cda6c3d2-1990-416d-89a3-9fb06605d27e
Local pid:
pubs:244477
Deposit date:
2012-12-19

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