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Artemisinin resistance in Plasmodium falciparum malaria.

Abstract:

BACKGROUND: Artemisinin-based combination therapies are the recommended first-line treatments of falciparum malaria in all countries with endemic disease. There are recent concerns that the efficacy of such therapies has declined on the Thai-Cambodian border, historically a site of emerging antimalarial-drug resistance. METHODS: In two open-label, randomized trials, we compared the efficacies of two treatments for uncomplicated falciparum malaria in Pailin, western Cambodia, and Wang Pha, no...

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Publication status:
Published

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Publisher copy:
10.1056/nejmoa0808859

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Institution:
University of Oxford
Department:
Oxford, MSD, Clinical Medicine, Thailand/Laos MOP
Role:
Author
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Journal:
The New England journal of medicine
Volume:
361
Issue:
5
Pages:
455-467
Publication date:
2009-07-05
DOI:
EISSN:
1533-4406
ISSN:
0028-4793
URN:
uuid:cda6a48c-d7e5-41f8-88ac-d418af6a1ee1
Source identifiers:
28011
Local pid:
pubs:28011

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