- Abstract:
-
Telomere length is a risk factor in disease and the dynamics of telomere length are crucial to our understanding of cell replication and vitality. The proliferation of whole genome sequencing represents an unprecedented opportunity to glean new insights into telomere biology on a previously unimaginable scale. To this end, a number of approaches for estimating telomere length from whole-genome sequencing data have been proposed. Here we present Telomerecat, a novel approach to the estimation ...
Expand abstract - Publication status:
- Published
- Peer review status:
- Peer reviewed
- Version:
- Publisher's Version
- Files:
-
-
(pdf, 2.1MB)
-
- Publisher copy:
- 10.1038/s41598-017-14403-y
-
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- Institution:
- University of Oxford
- Division:
- Medical Sciences Division
- Department:
- NDORMS
- Subgroup:
- KIR
- Role:
- Contibutor
- Publisher:
- Springer Nature Publisher's website
- Journal:
- Scientific reports Journal website
- Volume:
- 8
- Issue:
- 1
- Pages:
- Article: 1300
- Publication date:
- 2018-01-22
- Acceptance date:
- 2017-09-22
- DOI:
- EISSN:
-
2045-2322
- Pubs id:
-
pubs:822786
- URN:
-
uri:cd9b1513-18af-415a-a4f9-8e1b240b63c6
- UUID:
-
uuid:cd9b1513-18af-415a-a4f9-8e1b240b63c6
- Local pid:
- pubs:822786
- Language:
- English
- Copyright holder:
- Farmery et al.
- Copyright date:
- 2018
- Notes:
-
This version includes the publisher correction as indicated at: https://www.nature.com/articles/s41598-018-31524-0.
This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. Te images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.
Journal article
Telomerecat: a ploidy-agnostic method for estimating telomere length from whole genome sequencing data
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Authors
Contributors
+ Rue-Albrecht, K
Funding
Wellcome Trust
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