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The rapidly expanding CRF01_AE epidemic in China is driven by multiple lineages of HIV-1 viruses introduced in the 1990s.

Abstract:

OBJECTIVES: We sought to comprehensively analyze the origin, transmission patterns and sub-epidemic clusters of the HIV-1 CRF01_AE strains in China. METHODS: Available HIV-1 CRF01_AE samples indentified in national molecular epidemiologic surveys were used to generate near full-length genome (NFLG) sequences. The new and globally available CRF01_AE NFLG sequences were subjected to phylogenetic and Bayesian molecular clock analyses, and combined with epidemiologic data to elucidate the histor...

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Publication status:
Published

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Journal:
AIDS (London, England) More from this journal
Volume:
27
Issue:
11
Pages:
1793-1802
Publication date:
2013-07-01
DOI:
EISSN:
1473-5571
ISSN:
0269-9370
Language:
English
Keywords:
Pubs id:
pubs:414422
UUID:
uuid:cd9a4b51-45c9-4284-bf82-65ff64e98432
Local pid:
pubs:414422
Source identifiers:
414422
Deposit date:
2013-11-16

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