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Evidence for continued two-brood replication of Plasmodium falciparum in vivo during quinine treatment.

Abstract:

To investigate the relationship between fever and parasite clearance in falciparum malaria, we studied 54 adults with Plasmodium falciparum infections who were all treated with quinine. The median oral temperature profile showed peaks at 24 h intervals during the first 3 days. Although there was no equivalent pattern evident in the median parasite clearance curve, we hypothesize that small numbers of two distinct parasite broods continued to develop in antiphase through schizogony despite qui...

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Publication status:
Published

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Institution:
University of Oxford
Division:
MSD
Department:
NDM
Role:
Author
Journal:
Acta tropica
Volume:
89
Issue:
1
Pages:
41-45
Publication date:
2003-12-01
DOI:
EISSN:
1873-6254
ISSN:
0001-706X
Source identifiers:
32548
Language:
English
Keywords:
Pubs id:
pubs:32548
UUID:
uuid:cd98aa9a-fb7c-4d86-a316-86b48069c4af
Local pid:
pubs:32548
Deposit date:
2012-12-19

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