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Mutations in the hemochromatosis gene and the clinical outcome of multiple sclerosis.

Abstract:

Multiple sclerosis (MS) is a common inflammatory disease of the central nervous system unsurpassed for its variability in disease outcome. Given a possible role for dysregulation of iron metabolism in MS disease pathogenesis, we investigated whether or not mutations in the HFE gene influence the prognosis of the disease. A cohort of sporadic MS cases, taken from opposite extremes of the putative distribution of long-term outcome using the most stringent clinical criteria to date, was used to ...

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Publication status:
Published

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Institution:
University of Oxford
Division:
MSD
Department:
Physiology Anatomy & Genetics
Role:
Author
Journal:
Journal of neuroimmunology More from this journal
Volume:
203
Issue:
1
Pages:
104-107
Publication date:
2008-10-01
DOI:
EISSN:
1872-8421
ISSN:
0165-5728
Language:
English
Keywords:
Pubs id:
pubs:34337
UUID:
uuid:cd93649f-2300-49ac-bcda-f4419586943d
Local pid:
pubs:34337
Source identifiers:
34337
Deposit date:
2012-12-19

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