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The centriolar cartwheel structure: symmetric, stacked, and polarized

Abstract:

An accurate centriolar structure is crucial for organelle function, necessitating the existence of molecular mechanisms for the tight control of centriole assembly. Formation of an initial scaffold, the cartwheel, assists the correct placement of centriolar proteins during assembly and templates key structural parameters of the organelle. Past work illustrated how cartwheel and centriolar symmetry are linked, and grounded organelle symmetry and diameter to the properties of the centriolar pro...

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Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.1016/j.sbi.2020.08.007

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Institution:
University of Oxford
Division:
MSD
Department:
Biochemistry
Role:
Author
Publisher:
Elsevier
Journal:
Current Opinion in Structural Biology More from this journal
Volume:
66
Pages:
1-7
Publication date:
2020-09-18
Acceptance date:
2020-08-25
DOI:
ISSN:
0959-440X
Language:
English
Pubs id:
1128374
Local pid:
pubs:1128374
Deposit date:
2020-08-26

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