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Virus-induced cell-cell fusion as a driver of metastasis

Abstract:

Viral infection is thought to be responsible for 15% of all cancers and has previously been linked to cancer progression through the virus induced cell fusion theory of metastasis. This theory proposes that fusion of different cells may endow the result- ing hybrid cells with metastatic properties. I developed a number of measures that I applied to WGS data from 6,337 tumours to identify tumours in which cell fusion may have occurred. Based on these measures I identified 15 primary tumours...

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Role:
Supervisor
Role:
Supervisor
Role:
Supervisor
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Name:
Wellcome Trust
Funder identifier:
http://dx.doi.org/10.13039/100010269
Grant:
203852/Z/16/A
Programme:
Genomic Medicine and Statistics 4 Year PhD Programme
Type of award:
DPhil
Level of award:
Doctoral
Awarding institution:
University of Oxford
Language:
English
Keywords:
Subjects:
Deposit date:
2021-09-14

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