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Journal article

Macrophages increase microparticle uptake by enterocyte-like Caco-2 cell monolayers.

Abstract:

Caco-2 cells form an enterocyte-like monolayer that has been used to explore small intestinal microparticle uptake. They are a useful functional model for the investigation of in vivo drug delivery systems and the uptake of particulate environmental pollutants. The aim of this paper was to determine if the previously reported decrease in Caco-2 transepithelial resistance following exposure to macrophages was matched by increased microparticle uptake, especially as macrophage phagocytosis simu...

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Publication status:
Published

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Institution:
University of Oxford
Division:
MSD
Department:
Physiology Anatomy & Genetics
Role:
Author
Journal:
Journal of anatomy
Volume:
217
Issue:
6
Pages:
740-754
Publication date:
2010-12-01
DOI:
EISSN:
1469-7580
ISSN:
0021-8782
Source identifiers:
114070
Language:
English
Keywords:
Pubs id:
pubs:114070
UUID:
uuid:cd752055-f3ec-4955-99b9-b495f5ed6914
Local pid:
pubs:114070
Deposit date:
2012-12-19

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