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Journal article

Induction of regulatory T cells and dominant tolerance by dendritic cells incapable of full activation.

Abstract:

Transplants tolerated through a process known as infectious tolerance evoke continuous recruitment of regulatory T (Treg) cells that are necessary to maintain the unresponsive state. This state is maintained long-term and requires continuous Ag exposure. It is not known, however, whether infectious tolerance operates through sustained recruitment of pre-existing regulatory cells, induction of regulatory cells, or both. Using mice deficient in natural Treg cells, we show here that quiescent do...

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Publication status:
Published

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Publisher copy:
10.4049/jimmunol.179.2.967

Authors


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Institution:
University of Oxford
Department:
Oxford, MSD, Pathology Dunn School
Role:
Author
More by this author
Institution:
University of Oxford
Department:
Oxford, MSD, Pathology Dunn School
Role:
Author
More by this author
Institution:
University of Oxford
Department:
Oxford, MSD, Pathology Dunn School
Role:
Author
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Journal:
Journal of immunology (Baltimore, Md. : 1950)
Volume:
179
Issue:
2
Pages:
967-976
Publication date:
2007-07-05
DOI:
EISSN:
1550-6606
ISSN:
0022-1767
URN:
uuid:cd6ca3ca-0367-4fe0-be1a-d1d732fa7b2a
Source identifiers:
28244
Local pid:
pubs:28244

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