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What is the importance of the immunological synapse?

Abstract:

The immunological synapse (IS) has proved to be a stimulating concept, particularly in provoking discussion on the similarity of intercellular communication controlling disparate biological processes. Recent studies have clarified some of the underlying molecular mechanisms and functions of the IS. For both T cells and natural killer (NK) cells, assembly of the IS can be described in stages with distinct cytoskeletal requirements. Functions of the IS vary with circumstance and include directi...

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Publisher copy:
10.1016/j.it.2004.03.007

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Institution:
University of Oxford
Department:
Oxford, MSD, NDORMS
Journal:
Trends in immunology
Volume:
25
Issue:
6
Pages:
323-327
Publication date:
2004-06-05
DOI:
EISSN:
1471-4981
ISSN:
1471-4906
URN:
uuid:cd55b6cf-d03a-4ace-8239-0e9caa0203ee
Source identifiers:
482631
Local pid:
pubs:482631

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