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Journal article

The importance of cellular immune response to HIV: implications for antibody production and vaccine design

Abstract:

Despite many years from the discovery of human immunodeficiency virus (HIV), a prophylactic vaccine against HIV is still needed. The failure of most of the vaccine clinical trials in the field has different causes, mainly due by the difficulties to identify the correct antigen able to prime the optimal B cell lineage and then make the series of somatic mutations necessary to generate broadly neutralizing antibodies (bNAbs). B cells are responsible for the bNAbs production; however, their func...

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Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.1089/dna.2021.0520

Authors


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Institution:
University of Oxford
Division:
MSD
Department:
NDM
Sub department:
Target Discovery Institute
Role:
Author
ORCID:
0000-0001-8492-5614
Publisher:
Mary Ann Liebert
Journal:
DNA and Cell Biology More from this journal
Volume:
41
Issue:
1
Pages:
38-42
Publication date:
2021-10-18
Acceptance date:
2021-08-14
DOI:
EISSN:
1557-7430
ISSN:
1044-5498
Pmid:
34664991
Language:
English
Keywords:
Pubs id:
1207499
Local pid:
pubs:1207499
Deposit date:
2021-12-04

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