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Inferring allele frequency trajectories from ancient DNA indicates that selection on a chicken gene coincided with changes in medieval husbandry practices.

Abstract:

Ancient DNA provides an opportunity to infer the drivers of natural selection by linking allele frequency changes to temporal shifts in environment or cultural practices. However, analyses have often been hampered by uneven sampling and uncertainties in sample dating, as well as being confounded by demographic processes. Here we present a Bayesian statistical framework for quantifying the timing and strength of selection using ancient DNA that explicitly addresses these challenges. We applied...

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Publication status:
Published
Peer review status:
Peer reviewed
Version:
Publisher's version

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Publisher copy:
10.1093/molbev/msx142

Authors


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Institution:
University of Oxford
Department:
Oxford, SSD, School of Archaeology, Archaeology Institute
Thomas, MG More by this author
More by this author
Institution:
University of Oxford
Department:
Oxford, SSD, School of Archaeology, Archaeology Institute
More by this author
Institution:
University of Oxford
Department:
Oxford, SSD, School of Archaeology, Archaeology Institute
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Grant:
647787-LocalAdaptation; ERC-2013-StG337574-UNDEAD
Publisher:
Oxford University Press Publisher's website
Journal:
Molecular Biology and Evolution Journal website
Volume:
34
Issue:
8
Pages:
1981–1990
Publication date:
2017-05-02
Acceptance date:
2017-04-17
DOI:
ISSN:
0737-4038 and 1537-1719
Pubs id:
pubs:691980
URN:
uri:cd2764ad-a81c-4949-8d67-f7abfa126599
UUID:
uuid:cd2764ad-a81c-4949-8d67-f7abfa126599
Local pid:
pubs:691980

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