Journal article icon

Journal article

Multiple QTL influence the serum Lp(a) concentration: a genome-wide linkage screen in the PROCARDIS study.

Abstract:

The serum concentration of lipoprotein Lp (a) is known to be highly heritable and associated with cardiovascular risk. A genome-wide variance component linkage analysis was performed to localise quantitative trait loci (QTLs) influencing Lp(a) levels in a large cohort collected in the PROCARDIS coronary heart disease study. Highly significant linkage was detected at the previously described LP(a) locus on chromosome 6q27 (LOD 108). Taking into account the effect of the locus detected on chrom...

Expand abstract
Publication status:
Published

Actions


Access Document


Publisher copy:
10.1038/sj.ejhg.5201732

Authors


More by this author
Institution:
University of Oxford
Division:
MSD
Department:
RDM
Sub department:
RDM Cardiovascular Medicine
Role:
Author
Journal:
European journal of human genetics : EJHG More from this journal
Volume:
15
Issue:
2
Pages:
221-227
Publication date:
2007-02-01
DOI:
EISSN:
1476-5438
ISSN:
1018-4813
Language:
English
Keywords:
Pubs id:
pubs:92412
UUID:
uuid:cd21e5e5-9695-464d-ad0c-eb3c6afed1c3
Local pid:
pubs:92412
Source identifiers:
92412
Deposit date:
2012-12-19

Terms of use


Views and Downloads






If you are the owner of this record, you can report an update to it here: Report update to this record

TO TOP