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Journal article

Pancreatic safety of sitagliptin in the TECOS Study.

Abstract:

Objective

We evaluated the incidence of acute pancreatitis and pancreatic cancer in patients with type 2 diabetes and cardiovascular disease treated with sitagliptin, a dipeptidyl peptidase-4 inhibitor (DPP-4i).

Research Design and Methods

In TECOS, a cardiovascular safety study of sitagliptin, all suspected cases of acute pancreatitis and pancreatic cancer were collected prospectively during 3 years’ median follow-up of 14,671 participants, and adjudicated blindl...

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Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.2337/dc15-2780

Authors


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Institution:
University of Oxford
Division:
MSD
Department:
RDM
Sub department:
OCDEM
Role:
Author
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Funding agency for:
Holman, R
Grant:
Senior Investigator
Merck and Co, Inc More from this funder
Publisher:
American Diabetes Association Publisher's website
Journal:
Diabetes Care Journal website
Volume:
40
Issue:
2
Pages:
164-170
Publication date:
2016-09-01
Acceptance date:
2016-07-28
DOI:
EISSN:
1935-5548
ISSN:
0149-5992
Source identifiers:
644347
Language:
English
Keywords:
Pubs id:
pubs:644347
UUID:
uuid:cd20efe8-80a2-459b-a9f3-01b583a0eac1
Local pid:
pubs:644347
Deposit date:
2017-05-30

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