Journal article icon

Journal article

A Comparative Structure/Function Analysis of Two Type IV Pilin DNA Receptors Defines a Novel Mode of DNA Binding.

Abstract:

DNA transformation is a widespread process allowing bacteria to capture free DNA by using filamentous nano-machines composed of type IV pilins. These proteins can act as DNA receptors as demonstrated by the finding that Neisseria meningitidis ComP minor pilin has intrinsic DNA-binding ability. ComP binds DNA better when it contains the DNA-uptake sequence (DUS) motif abundant in this species genome, playing a role in its trademark ability to selectively take up its own DNA. Here, we report hi...

Expand abstract
Publication status:
Published
Peer review status:
Peer reviewed

Actions


Access Document


Authors


More by this author
Institution:
University of Oxford
Division:
MSD
Department:
Pathology Dunn School
Role:
Author
More by this author
Institution:
University of Oxford
Division:
MSD
Department:
Pathology Dunn School
Role:
Author
More from this funder
Name:
Biotechnology and Biological Sciences Research Council
Publisher:
Cell Press
Journal:
Structure (London, England : 1993) More from this journal
Volume:
24
Issue:
6
Pages:
926-934
Publication date:
2016-05-05
Acceptance date:
2016-04-04
DOI:
EISSN:
1878-4186
ISSN:
0969-2126
Pmid:
27161979
Language:
English
Keywords:
Pubs id:
pubs:623082
UUID:
uuid:cd105804-901d-47b1-a047-5c4a49fc3bd3
Local pid:
pubs:623082
Source identifiers:
623082
Deposit date:
2016-10-25

Terms of use


Views and Downloads






If you are the owner of this record, you can report an update to it here: Report update to this record

TO TOP