- Abstract:
-
A sequence element located immediately upstream of the TATA element, and having the consensus sequence 5'-G/C-G/C-G/A-C-G-C-C-3', affects the ability of transcription factor IIB to enter transcription complexes and support transcription initiation. The sequence element is recognized directly by the transcription factor IIB. Recognition involves alpha-helices 4' and 5' of IIB, which comprise a helix-turn-helix DNA-binding motif. These observations establish that transcription initiation involv...
Expand abstract - Publisher copy:
- 10.1101/gad.12.1.34
-
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- Journal:
- Genes and development
- Volume:
- 12
- Issue:
- 1
- Pages:
- 34-44
- Publication date:
- 1998-01-05
- DOI:
- EISSN:
-
1549-5477
- ISSN:
-
0890-9369
- URN:
-
uuid:ccbe664a-eaf8-4adc-8cb4-b64a700053d9
- Source identifiers:
-
8231
- Local pid:
- pubs:8231
- Copyright date:
- 1998
Journal article
New core promoter element in RNA polymerase II-dependent transcription: sequence-specific DNA binding by transcription factor IIB.
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