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HD-PTP is a catalytically inactive tyrosine phosphatase due to a conserved divergence in its phosphatase domain.

Abstract:
The HD-PTP protein has been described as a tumor suppressor candidate and based on its amino acid sequence, categorized as a classical non-transmembrane protein tyrosine phosphatase (PTP). To date, no HD-PTP phosphorylated substrate has been identified and controversial results concerning its catalytic activity have been recently reported.

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Journal:
PLoS ONE More from this journal
Volume:
4
Issue:
4
Article number:
e5105
Publication date:
2009-01-01
ISSN:
1932-6203
Language:
English
Subjects:
UUID:
uuid:ccba5c41-4f56-41a4-8f72-c58125c1f656
Local pid:
SGC:19340315
Deposit date:
2011-08-18

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