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An estimate of the turnover rate of bone-derived plasma alkaline phosphatase in Paget's disease.

Abstract:
A through-knee amputation for suspected osteogenic sarcoma was performed on a patient with Paget's disease of the tibia. Plasma alkaline phosphatase (AP) activity fell to normal values, apparently as a single exponential function of time, with a half-life of 1.7 days. The daily turnover of bone-derived plasma AP was estimated to be approximately 200 I.U. from the Pagetic tibia and 20 I.U. from the rest of the skeleton.
Publication status:
Published

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Journal:
Clinica chimica acta; international journal of clinical chemistry More from this journal
Volume:
63
Issue:
2
Pages:
227-229
Publication date:
1975-09-01
DOI:
EISSN:
1873-3492
ISSN:
0009-8981
Language:
English
Keywords:
Pubs id:
pubs:109336
UUID:
uuid:cca2f946-bbb2-4138-b41e-e261e5dddca3
Local pid:
pubs:109336
Source identifiers:
109336
Deposit date:
2013-11-16

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