Journal article
Zfhx3 modulates retinal sensitivity and circadian responses to light
- Abstract:
-
Mutations in transcription factors often exhibit pleiotropic effects related to their complex expression patterns and multiple regulatory targets. One such mutation in the zinc finger homeobox 3 (ZFHX3) transcription factor, short circuit (Sci, Zfhx3Sci/+), is associated with significant circadian deficits in mice. However, given evidence of its retinal expression, we set out to establish the effects of the mutation on retinal function using molecular, cellular, behavioral and electrophysiolo...
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- Publication status:
- Published
- Peer review status:
- Peer reviewed
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Authors
Funding
Wellcome Trust
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Bibliographic Details
- Publisher:
- Federation of American Societies for Experimental Biology Publisher's website
- Journal:
- FASEB Journal Journal website
- Volume:
- 35
- Issue:
- 9
- Article number:
- e21802
- Publication date:
- 2021-08-12
- Acceptance date:
- 2021-07-01
- DOI:
- EISSN:
-
1530-6860
- ISSN:
-
0892-6638
- Pmid:
-
34383984
Item Description
- Language:
- English
- Keywords:
- Pubs id:
-
1192339
- Local pid:
- pubs:1192339
- Deposit date:
- 2022-03-07
Terms of use
- Copyright holder:
- Hughes et al
- Copyright date:
- 2021
- Rights statement:
- © 2021 The Authors. The FASEB Journal published by Wiley Periodicals LLC on behalf of Federation of American Societies for Experimental Biology. This is an open access article under the terms of the Creative Commons Attribution License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.
- Licence:
- CC Attribution (CC BY)
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