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Biomarkers of transplantation tolerance: More hopeful than helpful?

Abstract:

A major limitation to the translation of tolerogenic therapies to clinical transplantation is a lack of biomarkers that can be used as surrogate measures for predicting the successful induction of immune tolerance which would allow for the safe withdrawal of immunosuppression. We have used three different mouse models of donor specific tolerance to skin grafts together with quantitative RT-PCR to search for potential biomarkers of tolerance using criteria based on the presence or activity of ...

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Publisher copy:
10.3389/fimmu.2011.00009

Authors


Journal:
Frontiers in Immunology
Volume:
2
Issue:
APR
Pages:
1-8
Publication date:
2011-01-01
DOI:
EISSN:
1664-3224
URN:
uuid:cc876085-be69-49a1-ba35-37c3356c4a56
Source identifiers:
448413
Local pid:
pubs:448413

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