- Abstract:
-
Identification of correlates of protection for infectious diseases including malaria is a major challenge and has become one of the main obstacles in developing effective vaccines.We investigated protection against liver-stage malaria conferred by vaccination with adenoviral (Ad) and modified vaccinia Ankara (MVA) vectors expressing pre-erythrocytic malaria Ags. By classifying CD8+ T cells into effector, effector memory (TEM), and central memory subsets using CD62L and CD127 markers, we found...
Expand abstract - Publisher copy:
- 10.4049/jimmunol.1100302
-
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- Journal:
- Journal of Immunology
- Volume:
- 187
- Issue:
- 3
- Pages:
- 1347-1357
- Publication date:
- 2011-08-01
- DOI:
- EISSN:
-
1550-6606
- ISSN:
-
0022-1767
- URN:
-
uuid:cc84a91e-c13c-43b7-b169-b8deec8200dd
- Source identifiers:
-
179395
- Local pid:
- pubs:179395
- Language:
- English
- Copyright date:
- 2011
Journal article
CD8+ T effector memory cells protect against liver-stage malaria
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