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Journal article

Stress-related noradrenergic activity prompts large-scale neural network reconfiguration.

Abstract:

Acute stress shifts the brain into a state that fosters rapid defense mechanisms. Stress-related neuromodulators are thought to trigger this change by altering properties of large-scale neural populations throughout the brain. We investigated this brain-state shift in humans. During exposure to a fear-related acute stressor, responsiveness and interconnectivity within a network including cortical (frontoinsular, dorsal anterior cingulate, inferotemporal, and temporoparietal) and subcortical (...

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Publication status:
Published

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Publisher copy:
10.1126/science.1209603

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Journal:
Science (New York, N.Y.)
Volume:
334
Issue:
6059
Pages:
1151-1153
Publication date:
2011-11-05
DOI:
EISSN:
1095-9203
ISSN:
0036-8075
URN:
uuid:cc7d61f6-5e90-446b-8060-976679843e4c
Source identifiers:
216545
Local pid:
pubs:216545

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