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Mucosal healing as a target of therapy for colonic inflammatory bowel disease and methods to score disease activity.

Abstract:

Mucosal healing is an important therapeutic end point in clinical trials and clinical practice. There is no validated definition of mucosal healing in patients with inflammatory bowel disease, although the benefits of achieving mucosal healing include decreased need for corticosteroids, sustained clinical remission, decreased colectomy, and bowel resection. The Ulcerative Colitis Endoscopic Index of Severity is the only validated endoscopic index in ulcerative colitis. The Crohn's Disease End...

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Publication status:
Published
Peer review status:
Peer reviewed

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Institution:
University of Oxford
Division:
MSD
Department:
NDM
Sub department:
NDM Experimental Medicine
Role:
Author
Publisher:
Elsevier
Journal:
Gastrointestinal endoscopy clinics of North America More from this journal
Volume:
24
Issue:
3
Pages:
367-378
Publication date:
2014-07-01
DOI:
EISSN:
1558-1950
ISSN:
1052-5157
Language:
English
Keywords:
UUID:
uuid:cc7d317e-7f6f-4829-8e20-f6bf9ca60701
Local pid:
pubs:465517
Source identifiers:
465517
Deposit date:
2014-06-17

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