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Absence of association between cord specific antibody levels and severe respiratory syncytial virus (RSV) disease in early infants: A case control study from coastal Kenya

Abstract:

Background: The target group for severe respiratory syncytial virus (RSV) disease prevention is infants under 6 months of age. Vaccine boosting of antibody titres in pregnant mothers could protect these young infants from severe respiratory syncytial virus (RSV) associated disease. Quantifying protective levels of RSV-specific maternal antibody at birth would inform vaccine development.

Methods: A case control study nested in a birth cohort (2002-07) was conducted in Kilifi, Kenya; ...

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Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.1371/journal.pone.0166706

Authors


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Funding agency for:
Scott, J
Grant:
098532
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Funding agency for:
Nokes, D
Grant:
084633
More from this funder
Funding agency for:
Nokes, D
Grant:
084633
Publisher:
Public Library of Sciences Publisher's website
Journal:
PLoS ONE Journal website
Volume:
11
Issue:
11
Pages:
e0166706
Publication date:
2016-11-01
Acceptance date:
2016-11-02
DOI:
ISSN:
1932-6203
Source identifiers:
665079
Keywords:
Pubs id:
pubs:665079
UUID:
uuid:cc7acc5a-7630-44e8-8745-f247f5794453
Local pid:
pubs:665079
Deposit date:
2016-12-14

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