Journal article icon

Journal article

Differential gene expression profile reveals deregulation of pregnancy specific β1 glycoprotein 9 early during colorectal carcinogenesis

Abstract:

Background: APC (Adenomatous polyposis coli) plays an important role in the pathogenesis of both familial and sporadic colorectal cancer. Patients carrying germline APC mutations develop multiple colonic adenomas at younger age and higher frequency than non-carrier cases which indicates that silencing of one APC allele may be sufficient to initiate the transformation process.

Methods: To elucidate the biological dysregulation underlying...

Expand abstract
Publication status:
Published
Peer review status:
Peer reviewed

Actions


Access Document


Files:
Publisher copy:
10.1186/1471-2407-5-66

Authors


More by this author
Institution:
University of Oxford
Division:
MSD
Department:
RDM
Role:
Author
Publisher:
BioMed Central
Journal:
BMC Cancer More from this journal
Volume:
5
Article number:
66
Publication date:
2005-06-27
Acceptance date:
2005-06-27
DOI:
EISSN:
1471-2407
Language:
English
Keywords:
Pubs id:
pubs:122066
UUID:
uuid:cc77220f-d696-4d4d-9756-494b00a8d839
Local pid:
pubs:122066
Source identifiers:
122066
Deposit date:
2012-12-19

Terms of use


Views and Downloads






If you are the owner of this record, you can report an update to it here: Report update to this record

TO TOP