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Nonlinear diffusion of a growth inhibitory factor in multicell spheriods

Abstract:
A mathematical model is presented for the production of a growth inhibitory factor (GIF) within a multicell spheroid. The model is based on the assumption that the GIF diffuses within the spheroid in a nonlinear spatially dependent manner. This is in contrast with previous models, in which the nonlinearity was assumed in the production team. The results of the new model are compared with those of previous models and with experimental data.

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M. A. J. Chaplain More by this author
D. L. Benson More by this author
P. K. Maini More by this author
Publication date:
1994
URN:
uuid:cc6c542f-a41b-4a9c-a54f-599983d0f1ea
Local pid:
oai:eprints.maths.ox.ac.uk:496

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