Journal article
Chromophore-linked substrate (CLS405): Probing metallo-β-lactamase activity and inhibition
- Abstract:
-
Serine- and metallo-β-lactamases present a threat to the clinical use of nearly all β-lactam antibiotics, including penicillins, cephalosporins, and carbapenems. Efforts to develop metallo-β-lactamase (MBL) inhibitors require suitable screening platforms to allow the rapid determination of β-lactamase activity and efficient inhibition. Unfortunately, the platforms currently available are not ideal for this purpose. Further progress in MBL inhibitor identification requires inexpensive and wide...
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- Publisher copy:
- 10.1002/cmdc.201300350
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Authors
Bibliographic Details
- Journal:
- ChemMedChem
- Volume:
- 8
- Issue:
- 12
- Pages:
- 1923-1929
- Publication date:
- 2013-12-01
- DOI:
- EISSN:
-
1860-7187
- ISSN:
-
1860-7179
- Source identifiers:
-
444432
Item Description
- Language:
- English
- Keywords:
- Pubs id:
-
pubs:444432
- UUID:
-
uuid:cc521673-9be2-4dfc-9b21-59dd08511317
- Local pid:
- pubs:444432
- Deposit date:
- 2014-02-08
Terms of use
- Copyright date:
- 2013
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