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Maternal serum alpha-fetoprotein and previous neural tube defects.

Abstract:

A case-control study involving 63 pregnancies showed that women who had previously had an infant with anencephaly or spina bifida did not have raised serum alpha-fetroprotein (AFP) levels in subsequent unaffected pregnancies. The value of a serum AFP determination in such women is discussed. If the serum AFP level is normal and if ultrasonography excludes anencephaly the risk of spina bifida might be low enough (about 1 per cent) to make diagnostic amniocentesis difficult to justify. Converse...

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Publication status:
Published

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Institution:
University of Oxford
Division:
MSD
Department:
Nuffield Department of Population Health
Sub department:
Clinical Trial Service Unit
Role:
Author
Journal:
British journal of obstetrics and gynaecology
Volume:
83
Issue:
3
Pages:
213-216
Publication date:
1976-03-01
DOI:
EISSN:
1471-0528
ISSN:
0306-5456
Source identifiers:
41630
Language:
English
Keywords:
Pubs id:
pubs:41630
UUID:
uuid:cc42ef4c-cf22-4b7d-bf85-197ed33085e1
Local pid:
pubs:41630
Deposit date:
2012-12-19

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