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Journal article

Glucose and lactate kinetics in children with severe malaria.

Abstract:

Children with severe malaria often present with lactic acidosis and hypoglycemia. Although both complications independently predict mortality, mechanisms underlying their development are poorly understood. To study these metabolic derangements we sequentially allocated 21 children with falciparum malaria and capillary lactate concentrations of 5 mmol/L or more to receive either quinine or artesunate as antimalarial therapy, and dichloroacetate or saline placebo for lactic acidosis. We then ad...

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Publication status:
Published

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Publisher copy:
10.1210/jc.85.4.1569

Authors


Agbenyega, T More by this author
More by this author
Institution:
University of Oxford
Department:
Oxford, MSD, Clinical Medicine, Tropical Medicine
Bedu-Addo, G More by this author
Baffoe-Bonnie, B More by this author
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Journal:
The Journal of clinical endocrinology and metabolism
Volume:
85
Issue:
4
Pages:
1569-1576
Publication date:
2000-04-05
DOI:
EISSN:
1945-7197
ISSN:
0021-972X
URN:
uuid:cc411466-b5b0-46fe-b81f-59c917e1ecc6
Source identifiers:
37553
Local pid:
pubs:37553

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