PfHPRT: a new biomarker candidate of acute Plasmodium falciparum infection.

Journal article

Plasmodium falciparum is a protozoan parasite that causes human malaria. This parasitic infection accounts for approximately 655,000 deaths each year worldwide. Most deaths could be prevented by diagnosing and treating malaria promptly. To date, few parasite proteins have been developed into rapid diagnostic tools. We have combined a shotgun and a targeted proteomic strategy to characterize the plasma proteome of Gambian children with severe malaria (SM), mild malaria, and convalescent contro...

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Authors: Thézénas, M; Huang, H; Njie, M; Ramaprasad, A; Nwakanma, D

• Publication status: Published
• Journal: Journal of proteome research
• Volume: 12
• Issue: 3
• Pages: 1211-1222
• Publication date: 2013-03-01
• DOI: 10.1021/pr300858g
• EISSN: 1535-3907
• ISSN: 1535-3893
• Language: English
• Keywords: Humans; Tandem Mass Spectrometry; Animals; Hypoxanthine Phosphoribosyltransferase; Child; Chromatography, High Pressure Liquid; Malaria, Falciparum; Plasmodium falciparum; Amino Acid Sequence; Molecular Sequence Data; Sequence Homology, Amino Acid; Blood Proteins; Electrophoresis, Polyacrylamide Gel; Gambia