Journal article icon

Journal article

Dimeric architecture of the Hendra virus attachment glycoprotein: evidence for a conserved mode of assembly

Abstract:

Hendra virus is a negative-sense single-stranded RNA virus within the Paramyxoviridae family which, together with Nipah virus, forms the Henipavirus genus. Infection with bat-borne Hendra virus leads to a disease with high mortality rates in humans. We determined the crystal structure of the unliganded six-bladed beta-propeller domain and compared it to the previously reported structure of Hendra virus attachment glycoprotein (HeV-G) in complex with its cellular receptor, ephrin-B2. As observ...

Expand abstract
Publication status:
Published
Peer review status:
Peer reviewed

Actions


Access Document


Publisher copy:
10.1128/jvi.00317-10

Authors


More by this author
Institution:
University of Oxford
Division:
MSD
Department:
NDM
Sub department:
Structural Biology
Role:
Author
More by this author
Institution:
University of Oxford
Division:
MSD
Department:
Biochemistry
Role:
Author
More by this author
Institution:
University of Oxford
Division:
MSD
Department:
Biochemistry
Role:
Author
More by this author
Institution:
University of Oxford
Division:
MSD
Department:
NDM
Sub department:
Structural Biology
Role:
Author
More by this author
Institution:
University of Oxford
Division:
MSD
Department:
NDM
Sub department:
Human Genetics Wt Centre
Role:
Author
Publisher:
American Society for Microbiology Publisher's website
Journal:
Journal of virology
Volume:
84
Issue:
12
Pages:
6208-6217
Publication date:
2010-06-01
Acceptance date:
2010-03-25
DOI:
EISSN:
1098-5514
ISSN:
0022-538X
Source identifiers:
52630
Language:
English
Keywords:
Pubs id:
pubs:52630
UUID:
uuid:cc24aa72-4e70-4ef3-bc43-2a4be78c5ee7
Local pid:
pubs:52630
Deposit date:
2012-12-19

Terms of use


Views and Downloads






If you are the owner of this record, you can report an update to it here: Report update to this record

TO TOP