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Journal article

Cartilage oligomeric matrix protein is differentially expressed in human subcutaneous adipose tissue and regulates adipogenesis

Abstract:
Objective The composition of the extracellular matrix (ECM) impacts adipocyte function and might determine adipose tissue (AT) function and distribution. Cartilage oligomeric matrix protein (COMP), a matricellular protein usually studied in bone and cartilage, is highly differentially expressed between subcutaneous abdominal and gluteal AT. This study aimed to explore COMP's role in human subcutaneous abdominal and gluteal AT and preadipocyte biology. Methods Expand abstract
Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.1016/j.molmet.2018.07.005

Authors


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Institution:
University of Oxford
Division:
Medical Sciences Division
Department:
RDM
Sub department:
OCDEM
Role:
Author
More by this author
Institution:
University of Oxford
Division:
MSD
Department:
RDM
Sub department:
OCDEM
Oxford college:
Brasenose College
Role:
Author
ORCID:
0000-0002-2751-1770
More from this funder
Name:
British Heart Foundation
Grant:
RG/17/1/32663
More from this funder
Name:
NIHR Oxford Biomedical Research Centre
Publisher:
Elsevier
Journal:
Molecular Metabolism More from this journal
Volume:
16
Pages:
172-179
Publication date:
2018-07-27
Acceptance date:
2018-07-23
DOI:
ISSN:
2212-8778
Pmid:
30100245
Language:
English
Keywords:
Pubs id:
pubs:905841
UUID:
uuid:cc212886-6f26-4bc4-8a7b-df9a06e0881c
Local pid:
pubs:905841
Source identifiers:
905841
Deposit date:
2018-09-05

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