Journal article
High multiplicity HIV-1 cell-to-cell transmission from macrophages to CD4+ T cells limits antiretroviral efficacy
- Abstract:
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Few studies have examined the efficacy of antiretroviral therapy (ART) in the context of cell-to-cell transmission. We aimed to determine whether the activity of ART is limited by the mode of HIV-1 spread between cells and the type of immune cell implicated in transmission, or is independent of these variables.ART activity was evaluated in primary cells using in-vitro cell-free and cell to-cell HIV-1 infection systems.HIV-1 cell-free or cell-to-cell transmission between infected monocyte-deri...
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- Publication status:
- Published
- Peer review status:
- Peer reviewed
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Access Document
- Files:
-
-
(Accepted manuscript, pdf, 497.2KB)
-
- Publisher copy:
- 10.1097/qad.0b013e3283632ec4
Authors
Bibliographic Details
- Publisher:
- Lippincott, Williams & Wilkins Publisher's website
- Journal:
- AIDS Journal website
- Volume:
- 27
- Issue:
- 14
- Pages:
- 2201–2206
- Publication date:
- 2013-09-10
- DOI:
- EISSN:
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1473-5571
- ISSN:
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0269-9370
Item Description
- Language:
- English
- Keywords:
- Pubs id:
-
pubs:421086
- UUID:
-
uuid:cc16025f-5d46-4f13-b15f-b98b8354d932
- Local pid:
- pubs:421086
- Source identifiers:
-
421086
- Deposit date:
- 2013-11-16
Terms of use
- Copyright holder:
- Lippincott Williams & Wilkins, Inc
- Copyright date:
- 2013
- Notes:
-
This is an
accepted manuscript of a journal article published by Lippincott, Williams & Wilkins in AIDS on 2013-09-10, available online: http://dx.doi.org/10.1097/QAD.0b013e3283632ec4
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