- Abstract:
- 6 out of 7 patients with severe neutropenia associated with the use of amodiaquine for malaria prophylaxis amodiaquine (400 mg weekly) plus proguanil (200 mg daily); 1 of these patients had also taken cotrimoxazole and another had taken sulphaguanidine. The 7th patient had taken amodiaquine alone, but at a higher dose. A retrospective analysis suggests that the frequency of severe neutropenia complicating amodiaquine taken prophylactically may be as high as 1 in 2000.
- Publication status:
- Published
- Publisher copy:
- 10.1016/s0140-6736(86)92371-8
-
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- Journal:
- Lancet
- Volume:
- 1
- Issue:
- 8478
- Pages:
- 411-414
- Publication date:
- 1986-02-05
- DOI:
- EISSN:
-
1474-547X
- ISSN:
-
0140-6736
- URN:
-
uuid:cbe86e63-8222-49ea-9671-6466d17930d5
- Source identifiers:
-
196451
- Local pid:
- pubs:196451
- Language:
- English
- Keywords:
- Copyright date:
- 1986
Journal article
Frequency of severe neutropenia associated with amodiaquine prophylaxis against malaria.
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