[NiFe]-hydrogenases: spectroscopic and electrochemical definition of reactions and intermediates.

Journal article

Production and usage of di-hydrogen, H2, in micro-organisms is catalysed by highly active, 'ancient' metalloenzymes known as hydrogenases. Based on the number and identity of metal atoms in their active sites, hydrogenases fall into three main classes, [NiFe]-, [FeFe]- and [Fe]-. All contain the unusual ligand CO (and in most cases CN- as well) making them intriguing examples of 'organometallic' cofactors. These ligands render the active sites superbly 'visible' using infrared spectroscopy, w...

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Authors: Armstrong, F; Albracht, S

• Publication status: Published
• Journal: Philosophical transactions. Series A, Mathematical, physical, and engineering sciences
• Volume: 363
• Issue: 1829
• Pages: 937-954
• Publication date: 2005-04-01
• DOI: 10.1098/rsta.2004.1528
• EISSN: 1471-2962
• ISSN: 1364-503X
• Language: English
• Keywords: Hydrogen; Catalysis; Iron; Electric Power Supplies; Hydrogenase; Oxidation-Reduction; Electrochemistry; Spectrum Analysis; Models, Chemical; Nickel; Molecular Conformation