- Abstract:
-
We have previously reported that human T cell receptors (TcR) selected in the class II-restricted (HLA-DRB1*1302) response to a tetanus toxin peptide (tt830-843) frequently used the V beta 2 germ-line segment which paired with several V alpha segments and that the putative CDR3 of both alpha and beta chains showed remarkable heterogeneity. To analyze the structural basis for recognition of the tt830-843/DR complex, five of these TcR were reconstituted into a murine T cell hybridoma, 58 alpha-...
Expand abstract - Publication status:
- Published
- Publisher copy:
- 10.1002/eji.1830231203
-
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- Journal:
- European journal of immunology
- Volume:
- 23
- Issue:
- 12
- Pages:
- 3057-3065
- Publication date:
- 1993-12-05
- DOI:
- EISSN:
-
1521-4141
- ISSN:
-
0014-2980
- URN:
-
uuid:cbb2ba9e-a0a5-4742-a8d7-40f25ad7fff6
- Source identifiers:
-
11239
- Local pid:
- pubs:11239
- Language:
- English
- Keywords:
- Copyright date:
- 1993
Journal article
Analysis of tetanus toxin peptide/DR recognition by human T cell receptors reconstituted into a murine T cell hybridoma.
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