Journal article
Biological rationale and potential clinical use of gabapentin and pregabalin in bipolar disorder, insomnia and anxiety. Protocol for a systematic review
- Abstract:
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Introduction. Gabapentin has been extensively prescribed off-label for psychiatric indications, with little established evidence of efficacy. Both gabapentin and pregabalin, a very similar drug with the same mechanism of action, bind to a subunit of voltage dependent calcium channels, which are implicated in the aetiopathogenesis of bipolar disorder, anxiety and insomnia. This systematic review and meta-analysis aims to collect and critically appraise all the available evidence about effic...
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- Publication status:
- Published
- Peer review status:
- Peer reviewed
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- Files:
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(Version of record, pdf, 779.3KB)
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- Publisher copy:
- 10.1136/bmjopen-2016-013433
Authors
Bibliographic Details
- Publisher:
- BMJ Publishing Group Publisher's website
- Journal:
- BMJ Open Journal website
- Volume:
- 7
- Issue:
- 3
- Pages:
- 1-9
- Publication date:
- 2017-03-27
- Acceptance date:
- 2017-01-13
- DOI:
- ISSN:
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2044-6055
Item Description
- Pubs id:
-
pubs:672189
- UUID:
-
uuid:cbadb7f0-29be-45fa-b615-4d2128fd80e2
- Local pid:
- pubs:672189
- Deposit date:
- 2017-01-20
Terms of use
- Copyright holder:
- © Houghton, et al 2017
- Copyright date:
- 2017
- Notes:
- This is an Open Access article distributed in accordance with the terms of the Creative Commons Attribution (CC BY 4.0) license, which permits others to distribute, remix, adapt and build upon this work, for commercial use, provided the original work is properly cited. See: http://creativecommons.org/licenses/by/4.0/
- Licence:
- CC Attribution (CC BY)
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