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Increase in Hepatic NKT Cells in Leukocyte Cell-Derived Chemotaxin 2-Deficient Mice Contributes to Severe Concanavalin A-Induced Hepatitis

Abstract:

Leukocyte cell-derived chemotaxin 2 (LECT2) was originally identified for its possible chemotactic activity against human neutrophils in vitro. It is a 16-kDa protein that is preferentially expressed in the liver. Its homologues have been widely identified in many vertebrates. Current evidence suggests that LECT2 may be a multifunctional protein like cytokines. However, the function of LECT2 in vivo remains unclear. To elucidate the role of this protein in vivo, we have generated LECT2-defici...

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Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.4049/jimmunol.173.1.579

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Role:
Author
ORCID:
0000-0002-3977-6207
Publisher:
American Association of Immunologists
Journal:
Journal of Immunology More from this journal
Issue:
1
Publication date:
2004-06-21
Acceptance date:
2004-04-28
DOI:
EISSN:
1550-6606
ISSN:
0022-1767
Pmid:
15210819
Language:
English
Keywords:
Pubs id:
pubs:627593
UUID:
uuid:cbacd3e8-5e70-4303-8f4f-3296b348f628
Local pid:
pubs:627593
Source identifiers:
627593
Deposit date:
2018-03-05

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