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The nucleoplasmic reticulum form, formation, and function

Abstract:

Many primary cells, cell lines and cells in situ in tissues may have under certain circumstances a network of invaginations of the nuclear envelope. This network called the nucleoplasmic reticulum (NR) brings deep within the nucleus the conventional functions of the nuclear envelope such as anchorage and regulation of genetic material and transport of ions and macromolecular cargo. Abundant NR is a hallmark of cancer cells and senescence.


We hypothesised that the NR ma...

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Institution:
University of Oxford
Division:
MSD
Department:
Pathology Dunn School
Oxford college:
Lincoln College
Role:
Author

Contributors

Role:
Contributor
Role:
Contributor
Institution:
University of Oxford
Division:
MSD
Department:
Pathology Dunn School
Role:
Contributor
Role:
Contributor
Role:
Contributor



DOI:
Type of award:
DPhil
Level of award:
Doctoral
Awarding institution:
University of Oxford


Language:
English
Pubs id:
2017810
Local pid:
pubs:2017810
Deposit date:
2024-07-17

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