- Abstract:
-
Human immunodeficiency virus type 1 (HIV-1) genetic diversity is a major obstacle for the design of a successful vaccine. Certain viral polymorphisms encode human leukocyte antigen (HLA)-associated immune escape, potentially overcoming limited vaccine protection. Although transmission of immune escape variants has been reported, the overall extent to which this phenomenon occurs in populations and the degree to which it contributes to HIV-1 viral evolution are unknown. Selection on the HIV-1 ...
Expand abstract - Publication status:
- Published
- Publisher copy:
- 10.1128/jvi.02014-05
-
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- Journal:
- Journal of virology
- Volume:
- 80
- Issue:
- 14
- Pages:
- 7226-7234
- Publication date:
- 2006-07-05
- DOI:
- EISSN:
-
1098-5514
- ISSN:
-
0022-538X
- URN:
-
uuid:cb985a0b-0389-48bb-8088-d75a2aa13b78
- Source identifiers:
-
28051
- Local pid:
- pubs:28051
- Copyright date:
- 2006
Journal article
Passive sexual transmission of human immunodeficiency virus type 1 variants and adaptation in new hosts.
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