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Journal article

Passive sexual transmission of human immunodeficiency virus type 1 variants and adaptation in new hosts.

Abstract:

Human immunodeficiency virus type 1 (HIV-1) genetic diversity is a major obstacle for the design of a successful vaccine. Certain viral polymorphisms encode human leukocyte antigen (HLA)-associated immune escape, potentially overcoming limited vaccine protection. Although transmission of immune escape variants has been reported, the overall extent to which this phenomenon occurs in populations and the degree to which it contributes to HIV-1 viral evolution are unknown. Selection on the HIV-1 ...

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Publication status:
Published

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Publisher copy:
10.1128/jvi.02014-05

Authors


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Institution:
University of Oxford
Division:
MSD
Department:
NDM
Sub department:
NDM Experimental Medicine
Role:
Author
Journal:
Journal of virology More from this journal
Volume:
80
Issue:
14
Pages:
7226-7234
Publication date:
2006-07-01
DOI:
EISSN:
1098-5514
ISSN:
0022-538X
Language:
English
Keywords:
Pubs id:
pubs:28051
UUID:
uuid:cb985a0b-0389-48bb-8088-d75a2aa13b78
Local pid:
pubs:28051
Source identifiers:
28051
Deposit date:
2012-12-19

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