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Mixed treatment comparison and meta-regression of the efficacy and safety of prostaglandin analogues and comparators for primary open-angle glaucoma and ocular hypertension.

Abstract:

OBJECTIVES: Primary open-angle glaucoma (POAG) is a chronic condition characterised by optic neuropathy and vision loss. Elevated intraocular pressure (IOP) can damage the optic nerve and is a risk factor for glaucoma, thus treatment usually comprises topical hypotensives. This analysis aims to address methodological issues associated with the synthesis of glaucoma clinical trial data, given variations in study methodology and IOP measurement. METHODS: Meta-regression was used to estimate ho...

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Publication status:
Published

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Publisher copy:
10.1185/03007990903498786

Authors


Collins, S More by this author
Journal:
Current medical research and opinion
Volume:
26
Issue:
3
Pages:
511-528
Publication date:
2010-03-05
DOI:
EISSN:
1473-4877
ISSN:
0300-7995
URN:
uuid:cb967dc6-8055-434a-9e57-00c64c5d4624
Source identifiers:
64811
Local pid:
pubs:64811

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